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N chemical thermodynamics, an endergonic reaction (also called a nonspontaneous reaction or an unfavorable reaction) is a chemical reaction in which the standard change in free energy is positive, and energy is absorbed. In layman's terms, the total amount of energy is a loss (it takes more energy to start the reaction than what you get out of it) so the total energy is a negative net result. For an overall gain in the net result see exergonic reaction.
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