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An antigenic substance prepared from the causative agent of a disease or a synthetic substitute, used to provide immunity against one or several diseases....
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a vaccine is a preparation of killed weakened disease causing microbes.when a vaccine is injected into a body of healthy person his/her body produces antibodies against these killed of weaken microbes.thees antibodies  remain in the body and protect us from future infection by the same microbes.thus a vaccine help in preventing disease caused by microbes(eg, cholera,typhoid,smallpox and hepatitis) 
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