Answers

2016-01-10T21:25:00+05:30
When a pathogen enters in a body then it infects a particular tissue or an organ which causes disease. This is called organ specific manifestation. 

E.g, if the bacteria will enter through nose then it will infect the lungs which can cause T.B..
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2016-01-10T22:12:48+05:30
When PATHOGEN enters the body causes a severe disease and this is meaning of organ specific tissue
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