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It is an oxide that can act as either an acid or base in a reaction. example: Al2O3
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An amphoteric oxide is an oxide that can act both as an acid and as a base. An example is aluminium oxide, Al2O3. It reacts with acids to form the corresponding aluminium salt, and with bases to form salts called aluminates. 

Example reactions 

Al2O3 + 6HCl → 2AlCl3 + 3H2O 
Al2O3 + 2NaOH → Na2Al2O4 + H2O
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