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In Leishmania , binary fission occurs in a definite orientation :
1: nuclear division is followed by the appearance of a constriction in the cell membrane.
2:Membrane then grows transversely inward from near the middle of dividing cell.
3:Cytoplasm separates into two equal parts , each with one nucleus.
4:The two daughter cell may separate from each other and behave as two independent organisms.

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