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Single celled organisms (ex bacteria) don't die. instead, at the end of their life cycle, the cell divides into two daughter cells. Therefore, unless killed by some unnatural substance (ex extreme temperatures of germ-ex) the cells will continue to divide in two instead of die. that's why we say that single celled organisms don't die by natural death..
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We generally say that single celled organisms do not die. This is because most of the single celled species such as bacteria and amoeba undergo fission, a type of division, as a form of asexual reproduction. The mother cell, after attaining level of maturation, divides itself into two daughter cells. This way it does not perish, but transforms itself into new prodigy.

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