Natural fibres are derived from plants and animals, whereas synthetic fibres are almost entirely man made.
Fabrics made of natural fibres are generally more comfortable than synthetic ones.
Natural fibres are expensive compared to synthetic fibres.
In synthetic fibres, spinnerets are used to produce the filaments whereas, in natural fibres, it is naturally made.
Natural fibres have limited usage when compared to synthetic fibres.
Natural fibres are biodegradable hence environmentally friendly, unlike synthetic fibres.
eg. of natural fibre is cotton,silk
eg. of man made is polyester