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2014-06-07T16:54:11+05:30
Most probably Edward Jenner was the first to invent vaccine.
Two unicellular algae are:
Chlamydomonas
Desmid algae
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2014-06-07T16:59:43+05:30

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It depends on the disease for which the vaccine was discovered. But the earliest works regarding vaccination was done by Edward jenner.
Unicellular algae
chlorella
chlamydomonas
Spirogyra ( unicellular and filamentous )
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