Clotting factors are proteins in the blood that control bleeding. When a blood vessel is injured, the walls of the blood vessel contract to limit the flow of blood to the damaged area. Then, small blood cells called platelets stick to the site of injury and spread along the surface of the blood vessel to stop the bleeding.
At the same time, chemical signals are released from small sacs inside the platelets that attract other cells to the area and make them clump together to form what is called a platelet plug.
On the surface of these activated platelets, many different clotting factors work together in a series of complex chemical reactions to form a fibrin clot. The clot acts like a mesh to stop the bleeding.
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