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The mad cow disease is a fatal neurodegenerative disease in cattle that causes a spongy degenerationin the brain& spinal cord. the cow lose ability to stand
Abnormal proteins called prions are found in brain tissue of diseased cattle and appear to be the particle that transmits the infection. Characteristic changes are seen in the brain of infected cattle. Infection leads to tiny holes in parts of the brain, giving the tissue a sponge-like appearance when viewed with a microscope. These so-called spongy holes cause slow deterioration within the cow's brain and eventually other symptoms develop affecting the whole body. Death follows. :)