Phophet muhammad was born in mecca and o e he shifted to medina and frim that time these two places are the holy places od muslims.

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Muhammad was forced to leave Mecca as some of his teachings went against the established faith of the Arabs.He took refuge in a town called Yathrib now called Medina.This marks the beginning of Islamic era and the birth of Muslim community or Umma.
As Muhammad was at Mecca and Medina it was considered sacred as Muhammad was the Prophet of the Muslims. The Black Stone at KABBA,MEDINA is famous for pilgrims of the Muslims.Till now they go there to perform an event called HAJ.