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Brain -- located inside the cranial cavity or skull. Protected by the meninges. The most important internal organ in our body. Forms part of the central nervous system. Controls the activities of glands and other internal organs.

heart -- pumps blood and forms part of the circulatory system. It pumps oxygenated blood to all parts of the body and send the deoxygenated blood to the lungs.
BRAIN: Acts as center of nervous system
HEART: Acts as the body's circulatory Pump.