Obnoxious - means some one or something is - highly objectionable, annoying, attracting undue attention, irritate , disturb. Antonym is Delightful.
The obnoxious little brats irritate me every day.
Mitigate : means reduce the effect of something, to make something milder
One can do a lot of things to mitigate risks, but perhaps one cannot
eliminate them (risks). Government should do a lot of things to
mitigate the water shortage problem.
culminate : reaching a highest point of performance, reaching the final stage of doing
something, some towers culminate in a pyramidal shape. The various
functions and celebrations culminate in a classical dance or music program.