Mechanism of fluoride action in caries prevention

Fluoride treatment regimens have been developed to prevent dental caries. Systemic fluoride is easily absorbed and is taken up into the enamel during the period of pre- eruptive tooth formation. The predominant beneficial cariostatic effects of fluoride in erupted teeth occur locally at the tooth surface. This could be achieved by fluoridated toothpaste, fluoride-containing water, fluoridated salt, etc. maintaining elevated intra- oral fluoride levels of the teeth, dental biofilm and saliva throughout the day.