When a person does not eat for some time, he/she gets hunger pangs (contraction of stomach muscles inside) and pains. But hunger subsides some time after hunger pangs because:
The starvation response (adaptation of metabolism) of our
body takes care of energy supply to the cells during the absence of food.
During starvation period, the levels of insulin drops and the levels of
glucagon, epinephrine and norepinephrine increase in the circulating
blood. Starvation response causes an increase in the
processes glycogenolysis, gluconeogenesis (conversion of glycerol into glucose),
lipolysis (induced by many hormones including ghrelin) and ketogenesis. Also, Cori cycle converts lactate into
The body’s glycogen stores are consumed. Glucose is obtained from the breakdown of
stored glycogen in the liver and in muscle cells. So glucose levels in the blood rise again.
Also the free fatty acids from the body fat reserves are
As glucose levels go up, the hunger subsides.