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There is nothing like a best course.  Choice usually depends on one person's interest and ability and qualifying marks.  If u are very good in academics, then there are many choices available.  Even otherwise, there are many options available.

Engineering side
   B. Tech - bachelor of technology
   B. E. Bachelor of engineering
   Diploma - in a a polytechnic institute  - LME , LCE  licensed engineer and AMIE after
   Diploma - I T I -  Industrial technical institutes

Science side

   B Sc - bachelor of science - maths physics chemistry
   B Sc -                  - zoology, botany
   B Sc computer science
   diploma or degree in Home science
   Integrated MSc course -  5 year course

commerce side and arts side  -  one can change discipline to commerce and arts
   B Com - bachelor of commerce
   B A  - arts, 
   film technology,  fashion technology

Other courses

   career  in piloting airplanes
   B B A - bachelor of business administration
   N DA - national defence academy

Pharmacy and medicine
   B Pharm - bachelor of pharmacy
   D. pharm.  Diploma in pharmacy
   BDS - bachelor dental surgery
   MBBS - bachelor of medicine
   degree or diploma for Nursing
   degree in ayurveda,
     degree in homeopathy

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